Win32/Nuqel.E is a fake warning that is induced by a Trojan infection. If you are receiving messages related to this infection, it means that you are either have or will have soon one of the following rogue antispyware applications in your computer: Spyware Protect 2009, AV Security Suite, AntiSpyware Soft and Antivirus System Pro. These rogues have a lot of ways to get into your system, and these kinds of annoying Trojan generated messages are one of the ways that the rogues can use to reach you.
Here is an example of Win32/Nuqel.E
Spyware Protect 2009 alert
Your computer is being attacked by an internet virus. It could be a password-stealing attack, a trojan-dropper or similar.
DETAILS: Attack from 18.104.22.168, port 40771;
Attacked port 22363;
Do you want to block this attack?
Since Win32/Nuqel.E is a real threat, the previously mentioned rogues take advantage of it, and when they send these fake security notifications, the information that they give seems to be believable. Also, these messages are extremely annoying and pop up all the time, in order to convince you that you need to use one rogue antispyware program or the other to delete various threats from your computer. Win32/Nuqel.E makes it look like your computer has a lot of viruses, as the notifications little by little slows down your system and eventually you cannot avoid the full crash.
It is especially frustrating because Win32/Nuqel.E is hard to detect and remove. This message does not have an interface, nor is it represented by a process in your Windows Task Manager. If you do not know how to get rid of Win32/Nuqel.E manually, you should not try that, because you might accidentally delete an important DLL files and registry keys, thus rending your computer inoperable.
You should invest in a legitimate antimalware program that will be able to perform a full system scan, find all the components related to this infection and remove Win32/Nuqel.E for you automatically. What is more, with a security program of your choice you will be able to protect your computer from similar threats in the future, so do not hesitate any longer and deal with this infection right now.